CORRESPONDENCE BETWEEN STATIC AND DYNAMIC PROPERTIES IN A BIOCHEMICAL NETWORK

picture of John Andrews presenting his/her poster: CORRESPONDENCE BETWEEN STATIC AND DYNAMIC PROPERTIES IN A BIOCHEMICAL NETWORK

John Andrews , Erin S. Morrison, Alexander V. Badyaev

CORRESPONDENCE BETWEEN STATIC AND DYNAMIC PROPERTIES IN A BIOCHEMICAL NETWORK

Biological function is underlined by the static structure of its biochemical network and the network’s dynamic properties, such as rate of enzymatic transformations and changes in concentration. Thus, an understanding of the correspondence between static and dynamic properties of biochemical networks is crucial for deciphering their contribution to biological function. In this study we identified the functional modules in a biochemical network which produces carotenoids for feather coloration in birds. We constructed biochemical networks based on compounds found in the plumage of 37 house finch (Haemorhous mexicanus) females. We then examined the relationship between functional modules of these females and their static structural properties. We test whether the highly variable expression of carotenoid compounds in female feathers is caused by regulation of functional modules or structural position of these modules in the species’ biochemical network. These findings will further enhance our understanding of the biochemical mechanisms that underlie avian carotenoid coloration diversification. Support for this research comes from the National Science Foundation and from the Undergraduate Biology Research Program at the University of Arizona.

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