DIFFERENTIATION POTENTIAL OF MESENCHYMAL STEM CELLS ISOLATED FROM CRYOPRESERED HUMAN ADIPOSE AND CORD TISSUES.

Briana Choi , Mahmood S. Choudhery, Michael S. Badowski, Jorge Alvarez, Shery Park. Jeff Parrish, Angela Muise, Whitney Williams, Lisa White, Faryal Shareef, Hee Ju, David T. Harris.

DIFFERENTIATION POTENTIAL OF MESENCHYMAL STEM CELLS ISOLATED FROM CRYOPRESERED HUMAN ADIPOSE AND CORD TISSUES.

Mesenchymal stem cells (MSCs) have great potential for applications in regenerative medicine. MSCs are isolated from adult sources such as bone marrow and adipose tissue as well as newborn tissues such as umbilical cord blood, cord tissue, amniotic fluid and the placenta. Harvesting MSCs from human adipose and cord tissue is a non-invasive procedure and poses no risk to the donor. Family stem cell banks offer the opportunity to cryopreserve these tissues as a source of MSCs for future stem cell based regenerative medicine applications. There is little published data characterizing MSCs isolated from cryoperserved tissues. The goal of this study was to determine if MSCs isolated from cryopreserved adipose and cord tissues are functionally equivalent to MSCs isolated from fresh equivalent.

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