I began undergraduate research under the direction of Dr.
Michael A. Riehle in the summer of 2007. Dr.
Riehle has an appointment in Entomology and BIO5 at
the University of Arizona studying how some biochemical pathways
impact the lifespan and fecundity of mosquitoes. In December
2008, I left Sky Harbor Airport to attend my first science
conference in New
Orleans - The American Society of Tropical Medicine and Hygiene
Annual Conference. The trip was long anticipated
since my abstract had been accepted in late May and my poster
presentation set by September. While I was there, my goal
was to compete for a Young Investigators Award, present a
poster of my research, and become acquainted with the active
research interests surrounding tropical medicine.
My poster detailed the effects of overstimulation of the
insulin-signaling pathway on the lifespan of the malaria
vector, Anopheles stephensi. My lab designed a transgenic
line of An. Stephensi that overexpressed the protein Akt
- a key molecule in the pathway. Our results indicated that
our transgenic mosquitoes experienced a significant reduction
in lifespan. This was a significant finding because shorter-lived
mosquitoes provide less time for the development of the malaria
parasite. My poster was first presented to a panel of five
judges during the Young Investigators Award competition.
I was competing against thirteen individuals ranging in educational
level from graduate studies to post-doctoral research. The
realization of being the only undergraduate was initially
overwhelming, and I felt unprepared to present my entire
collection of data in a five-minute period with two minutes
left for questions. Shortly after the competition I received
feedback that I had competed comparably with the other investigators
and was ranked in the top six presenters.
My second presentation occurred during one of the daily
poster sessions. The atmosphere was much more relaxed, and
I found myself falling into discourse with many fellow scientists
following similar research paths. During the session I received
nice compliments on my work, including offers for both a
graduate research assistantship and a summer internship.
Once my presentations were completed, I was able to relax
and focus on other aspects of the conference. The conference
was well attended, with visitors coming from all areas of
the world to unite in the common interest of solving tropical
diseases. One of the most striking differences was the variation
in means to solve these global dilemmas. Research was split
between parasite and vector studies and ranged in approach
from molecular biology to epidemiology. Each talk was ten
minutes - just long enough to allow a glimpse at one scientist's
research emphasis. I was entering from a very focused viewpoint.
I know about mosquitoes and about insulin signaling - but
when it came to discussion of metabolic pathways of the plasmodium,
I was lost. The wide range of topics at the conference made
me realize the scope of possibility under the title "tropical
medicine" and view thousands of people come together
under that umbrella.
As I toured various colloquiums and listened to talks ranging
from mosquitoes, to worms, to single cell eukaryotes, I was
able to meet scientists in these varying fields. The most
rewarding were graduate students. It was energizing to meet
people so stimulated by the fields they work in and know
that I am nearing that next step in my career. I was able
to sit and discuss both the excitement and hardship of being
a graduate student. These discussions allowed my to see what
my life would be like if I were to choose to attend graduate
school in the sciences.
I returned to Tucson and finals week. Although flooded with
the prospect of returning to a hectic end of the semester,
I couldn't help but feel hopeful. The experience of attending
a conference and sharing my research made me certain that
I want to have a career in research science.
Laurel Watkins, UBRPer formerly in Dr. Michael Riehle's
lab, Entomology; now in Dr. Jean-Marc Fellous's lab, Neural
Systems, Memory and Aging