... began the moment I stepped off the plane. With my poster
in one hand and luggage in another, the intent of my visit
was obvious: to participate in the 231st National
American Chemical Society Meeting. This would be my first professional
conference where I would have to present a poster, which
made me both excited and nervous. Thinking about what was
in store for me, I proceeded from the airport to the Highland
Inn Hotel.
The next morning, in slightly cool rainy weather, I set off
for downtown Atlanta. Downtown Atlanta was very beautiful,
especially Centennial Olympic Park with the trees in bloom
and a fountain that danced to music. Water would spray up
from the fountain in pulses, and the pulses were coordinated
with the beat of music. The Georgia World Congress Center
was only a few feet away. The massive building was completely
filled with people hustling from one end to the other. I
browsed through the 325-page program, trying to make out
the 8-point font. I decided to limit my choices to the inorganic
division. Even after this reduction, deciding was still difficult.
I ended up making my first two days much more jam-packed
than I had anticipated.
For the first couple days, I would arrive at the convention
center at around 8:00 am and attend various talks until 5:00
pm. I would then go to dinner only to be back at the convention
center at 7:00 pm for the poster sessions. My tired self
would return to the hotel close to 11:00 pm. However, the
intriguing lectures were definitely worth the fatigue. The
amount of material I learned was extraordinary, and it would
take pages to summarize. So, to give a brief idea of the
kinds of talks I heard, I will elaborate on a few.
The very first talk I attended was titled "Platinum-DNA
structural and mechanistic chemistry at the nucleosome level." S.
Lippard was the speaker. He discussed platinum complexes,
such as cisplatin, oxaliplatin, and carboplatin, and their
uses as antitumor drugs. These complexes induce apoptosis
of the tumor cell by binding to the DNA of the cell and inhibiting
transcription and DNA replication.
H. B. Gray discussed such intriguing subjects as electron
tunneling and hopping, and how electron transfer triggers
protein folding in his presentation, "Mapping heme protein
folding landscapes." In addition, he discussed possible
electronic coupled pathways, which included hydrogen bonding.
His work involved using photochemical methods to trigger
protein folding, and observing the folding through absorption
spectroscopy.
Another interesting talk given by T. Ren entitled "Supramolecular
chemistry based on Ru2-alkynyl building blocks." He
discussed the electrochemical properties of various Ru2-alkynyl
complexes, and the possibility of creating molecular wires
with these ruthenium complexes. During the question session,
an older man challenged some of Ren's conclusions, which
reminded me of a great merit in the culture of science: peer
review.
After listening to other people communicate their research,
I was anxious to present mine. On Tuesday evening, I arrived
at the poster locale 15 minutes before the session was to
start. Right after hanging my poster, people began to come
and ask me questions. The title of my poster was "Coupled
Electron Proton Processes at Oxo-Molybdenum Center." I
discussed the goal of my experiment, which was to determine
pKa values of coordinated H2O and OH ligands of Oxo-Molybdenum
complexes. These pKa values are important for understanding
the catalytic cycle of sulfite oxidase, an enzyme that catalyzes
the oxidation of sulfite to sulfate, the last step in sulfur
metabolism. I proceeded to discuss my experimental methods,
which involved cyclic voltammetry and EPR to investigate
the effect of varying Brønstead acids on the electrochemical
reduction of oxo-molybdenum complexes. Subsequently, I explained
to the audience my electrochemical and EPR data. I was a
little nervous at first, but I became more comfortable over
the course of the evening. It was a great experience, discussing
my research and gaining new ideas and insight from others.
I had a fantastic time.
The moment finally came for me to leave. I packed my bags,
checked into the airport, and boarded the plane. Looking
out of the plane window, I was comforted with the memory
of my trip. In such a sort time, I had learned so much, and
had gained wonderful acquaintances and friends. It had been
incredible, and slightly surreal, to be under one roof with
thousands of scientists sharing their research. As the plane
landed, I thought about how grateful I was to have been given
the opportunity for this experience.
Rae Ana Snyder, Beckman Scholar, Dr. John Enemark's lab,
Chemistry